Bariatric surgery brings new hope for obese diabetic patients
Published March 5, 2013
A study conducted at Cleveland Clinic, Cleveland, Ohio reveals success of bariatric procedure in showing durable glycemic control up to two years. The results have been published online in Diabetes Care. In the past decade, surgical approaches for the treatment of obesity have increased. Also, previous studies have demonstrated improved glycemic control in patients undergoing bariatric surgery compared with intensive medical therapy (IMT).
During the study Dr. Kashyap and team randomly assigned 60 people with uncontrolled type 2 diabetes to undergo treatment with either IMT alone or in combination with Roux-en-Y gastric bypass or sleeve gastrectomy. The patients included in the study were moderately obese (BMI 36 kg/m2).
The researchers studied the glycemic control and reduction in body fat in all the patients, after 12 and 24 months. At the end of 24 months mean HbA1c (indication of glycemic control) was 6.7% for gastric bypass, 7.1% for sleeve gastrectomy, and 8.4% for IMT (the desired range in diabetes: at or below 6.5 - 7%.) In addition, gastric bypass procedure showed greater reduction in abdominal fat, increased insulin sensitivity and increased pancreatic ß-cell function, thus reversing the core defects in diabetes.
The results of this interesting study present that, bariatric surgery appears to be a good therapeutic option in obese diabetic patients who are not responding to other currently available drug therapies.
Kashyap SR, Bhatt DL. Metabolic Effects of Bariatric Surgery in Patients With Moderate Obesity and Type 2 Diabetes Analysis of a randomized control trial comparing surgery with intensive medical treatment. Diabetes Care Publish Ahead of Print, published online February 25, 2013. http://care.diabetesjournals.org/content/early/2013/02/14/dc12-1596.abstract Accessed on March 3, 2013.